Olaf Stapledon was a man ahead of his time. His epic 'novel' Star Maker (1937) considered the emergence of genetic engineering, the outcome of the many worlds interpretation and delved deeper than any book before or since into the consequences of evolution on the cosmos. His fans have included the likes of Arthur C Clarke, Jorge Luis Borges and Virginia Woolf. Even his greatest detractor, C.S.Lewis, wrote an entire Cosmic Trilogy in response to his imaginings. Yet despite Stapledon's magnetic prose and extraordinary influence on speculative fiction his name remains largely forgotten by the world.
(lots of links - I need to read this guy after Bester.)